A BMW failed to stop for police on Rochdale Road East, Heywood, at about 11:45pm on Sunday 20 March 2022.
A short pursuit took place and the BMW crashed into a building on Rochdale Road East.
Two men - aged 27 and 18 - were treated at the scene by police officers and then by paramedics. Both males are in a serious condition in hospital.
The incident has been referred to the Independent Office for Police Conduct.
Anyone with information or dashcam footage should call GMP's Serious Collision Investigation Unit on 0161 856 4741 quoting incident log 3178 of 20/03/22.
Information can also be reported online or by using the LiveChat function at www.gmp.police.uk. If you can't report online, call 101 or Crimestoppers anonymously on 0800 555 111.
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