The money was recovered from three safes that were found at a property on Mossfield Road in Kearsley.
Officers from Bolton’s Challenger organised crime team raided the house in the early hours of Thursday 27 April.
A 32-year-old man was led away in handcuffs after being arrested on suspicion of being concerned in the supply of class A and class B drugs and money laundering. He is now in police custody waiting to be questioned by detectives.
Detective Sergeant Paul Quinn said: “This morning we seized a substantial amount of cash and arrested a man in our continuing pursuit of criminals suspected of being linked to serious and organised crime.
“We rely on the eyes and ears of our local community to recognise the signs of drug activity occurring in their neighbourhood and reporting what you deem to be suspicious, and just like today, we will act on it.
“Any information you have – no matter how small – can be reported anonymously by contacting Crimestoppers on 0800 555 111 or GMP via 101.”
Further information related to serious and organised crime can be found here